Nurofen Day & Night Cold & Flu contains ibuprofen and pseudoephedrine hydrochloride, which is effective in relieving the symptoms associated with colds and flu, including relief of aches and pains, sore throats, headache, nasal congestion (blocked nose) and lowering of temperature. Ibuprofen belongs to a group of medicines known as non-steroidal anti-inflammatory drugs (NSAIDs) and is effective against aches and pains (including headache), swelling and can also reduce a fever. Phenylephrine hydrochloride (nasal decongestant) reduces swelling in the passages of the nose, relieving nasal congestion and reducing the pressure which may cause a headache.