Hedex Extra can provide extra relief from headache including migraine. They can also relieve backache, rheumatic and muscle pain, toothache, sore throat, period pain, and relieve the fever, aches, and pains of colds and flu. The tablets contain two active ingredients. Paracetamol is a painkiller and also reduces your temperature when you have a fever. Caffeine acts to further help the effectiveness of paracetamol.